Multislice Multiecho T2* MRI assessment of regional pancreatic iron overload and correlation with cardiac biventricular function and myocardial iron overload in thalassemia major patients

نویسندگان

  • G. Restaino
  • A. Meloni
  • A. Pepe
  • V. Positano
  • M. Missere
  • P. Pepe
  • D. De Marchi
  • G. Secchi
  • A. Luciani
  • G. Sallustio
  • M. Lombardi
چکیده

Introduction: Thalassemia major (TM) patients require lifelong iron load monitoring to assess the effectiveness of chelation therapies. Multiecho T2* MRI is a well established technique for heart and liver iron overload assessment [1]. There are few reports on the use of MRI to study iron deposits in the pancreas. The aims of this study were to describe the T2* values of the pancreas in patients with TM, to investigate the correlation between pancreatic and myocardial siderosis and to investigate the correlation between pancreatic iron overload and biventricular cardiac function.

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تاریخ انتشار 2009